Technologies

Imaging- and sequencing-based spatial transcriptomics and proteomics, single-cell and single-nucleus profiling, super-resolution microscopy, and tissue microarray construction. Select a platform for its specifications and workflow.

Xenium - 10x

Xenium is imaging-based spatial transcriptomics at sub-cellular resolution, on FFPE or fresh frozen tissue.

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Visium / Visium HD - 10x

Visium is a sequencing-based spatial gene expression platform from 10x Genomics that maps whole-transcriptome expression across an intact tissue section while preserving spatial context.

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GEM-X 3'/5'

GEM-X Single Cell Gene Expression is a droplet-based single-cell platform from 10x Genomics that profiles the whole transcriptome of individual cells or nuclei.

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Flex

Flex (Fixed RNA Profiling) is a probe-based single-cell gene expression assay from 10x Genomics for fixed cells and nuclei, including formaldehyde-fixed material and FFPE tissue.

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Epi Multiome

Epi Multiome (10x Chromium) simultaneously measures 3' gene expression and open chromatin (ATAC) from the same single nucleus, linking each cell's transcription to its regulatory landscape.

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Epi ATAC

Epi ATAC (10x Chromium) profiles genome-wide chromatin accessibility in single cells, mapping open regulatory regions and transcription-factor motif accessibility.

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StrataMap - Illumina

StrataMap (Illumina) is a sequencing-based spatial transcriptomics assay at 1 um resolution with very high sensitivity, capturing the whole transcriptome directly from the tissue section.

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G4X - Singular

G4X (Singular Genomics) is an in situ spatial multiomics platform that measures RNA, protein, and tissue morphology from a single FFPE section in one run, at subcellular resolution.

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MERSCOPE

The Spatial Technologies Unit operates a MERSCOPE (Vizgen), an imaging-based single-cell spatial transcriptomics platform built on MERFISH (Multiplexed Error-Robust Fluorescence in situ Hybridization).

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GeoMx - Bruker

The GeoMx Digital Spatial Profiler (Bruker) is a region-of-interest, morphology-guided spatial profiling platform for formalin-fixed paraffin-embedded (FFPE) and fresh-frozen tissue sections.

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Vutara - Bruker

Bruker Vutara VXL is a super-resolution 3D microscope using single-molecule localization microscopy (SMLM) with patented bi-plane detection.

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PhenoCycler-Fusion

PhenoCycler (PhenoCycler-Fusion) is an imaging-based spatial proteomics platform from Quanterix, formerly Akoya Biosciences; Quanterix completed its acquisition of Akoya in 2025.

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PhenoImager HT

PhenoImager HT is an imaging-based multiplex immunofluorescence platform from Quanterix (formerly Akoya Biosciences).

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STAMP

Single-cell in situ profiling of dissociated cells or nuclei, 50,000 to 100,000 per sample, run on a host spatial platform.

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Epredia / 3DHISTECH TMA GrandMaster

Tissue microarray construction on the 3DHISTECH TMA Grand Master.

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