Publications

Work supported by the Spatial Technologies Unit spans single-cell, spatial, and multi-omic profiling across oncology, immunology, and neurodegeneration. Titles and author lists are drawn from PubMed and link to the PubMed record; preprints are noted. Listed newest first.

Ohlstrom DJ, Pilcher WC Jr, Michaud ME, et al. Longitudinal Profiling of Tumor and Immune Compartments Uncovers Patterns of Dysregulation and Associations with Response in Multiple Myeloma. Blood Cancer Discovery. 2026.

Rai A, Iatrou A, Arzeta IV, et al. Aging-related Transcriptomic Changes with Spatial Resolution in the Human Prefrontal Cortex. bioRxiv [Preprint]. 2026.

Pilcher WC, Yao L, Gonzalez-Kozlova E, et al. A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma. Nature Cancer. 2026.

Liegel J, Stroopinsky D, Cheloni G, et al. Vaccine-educated T cells and a CD123 bispecific T-cell engager for treatment of acute myeloid leukemia. Blood Advances. 2025.

Sumpio BJ, Yeo K, Theocharidis G, et al. Integrated machine learning analysis of proteomic and transcriptomic data identifies healing associated targets in diabetic wound repair. Scientific Reports. 2025.

Castanho I, Naderi Yeganeh P, Boix CA, et al. Molecular hallmarks of excitatory and inhibitory neuronal resilience to Alzheimer's disease. Molecular Neurodegeneration. 2025.

Carvalho FL, Lee J, Kalavros N, et al. Tumor-myeloid crosstalk drives therapy resistance in localized bladder cancer. bioRxiv [Preprint]. 2025.

Valsami EA, Chu G, Guan M, et al. The Role of Omics Techniques in Diabetic Wound Healing: Recent Insights into the Application of Single-Cell RNA Sequencing, Bulk RNA Sequencing, Spatial Transcriptomics, and Proteomics. Advances in Therapy. 2025.

Cheloni G, Karagkouni D, Pita-Juarez Y, et al. Durable response to CAR T is associated with elevated activation and clonotypic expansion of the cytotoxic native T cell repertoire. Nature Communications. 2025.

Börner K, Blood PD, Silverstein JC, et al. Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas construction and usage. Nature Methods. 2025.

Plummer JT, Vlachos IS, Martelotto LG. Introducing the Global Alliance for Spatial Technologies (GESTALT). Nature Genetics. 2025.

Long X, Sharkey C, Ge R, Wang S, et al. Stem-like prostate remodeling in obesity mediates resistance to 5α-reductase inhibition therapy in BPH. bioRxiv [Preprint]. 2025.

Wang T, Roach MJ, Harvey K, et al. snPATHO-seq, a versatile FFPE single-nucleus RNA sequencing method to unlock pathology archives. Communications Biology. 2024.

Zhang Y, Naderi Yeganeh P, Zhang H, et al. Tumor editing suppresses innate and adaptive antitumor immunity and is reversed by inhibiting DNA methylation. Nature Immunology. 2024.

Immune profiling reveals distinct features of multiple myeloma subtypes defined by multi-omics network analysis. Blood. 2024.

Integrated coding and non-coding transcriptional single-cell atlas of multiple myeloma. Blood. 2024.

Unveiling the tumor microenvironment in extranodal NK/T-cell lymphoma with in situ spatial transcriptomics. Blood. 2024.